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treeko [2013/06/04 09:18] (current)
mmarcet created
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 +Comparisons between tree topologies provide important information for many evolutionary studies. TreeKo is a method that allows the **comparison of any two tree topologies**,​ even those with missing leaves and duplications. This is important in **genome-wide analysis** since many trees do not have exact leaf pairings and therefore most tree comparison methods are rendered useless.
 +In order to calculate the distance between two trees that contain duplications,​ **treeKo first prunes the trees** so that you obtain a list of trees that only contain one-to-one orthologs. Each collection of pruned trees is then compared to the other and two distances are calculated depending on whether the presence of duplication and loss events are considered a difference or not.
 +  * [[documentation|How to run treeKO]]
 +  * [[Algorithm|Algorithm]]
 +  * [[inputfiles|Input Files]]
 +  * [[output | Output Files]]
 +  * [[configuration_file | Configuration File]]
 +  * [[downloads|Downloads]]
 +  * [[about | About]]
treeko.txt ยท Last modified: 2013/06/04 09:18 by mmarcet